Pharmacy Startup Cost Comparison

Chicago, IL vs San Francisco, CA

Chicago, IL

$323,000 - $1,710,000

COL Index: 107.8

VS

San Francisco, CA

$431,000 - $2,275,000

COL Index: 179.8

Detailed Cost Comparison

Expense Chicago, IL San Francisco, CA Difference
Licensing & DEA Registration
$5,600 - $20,000 $5,000 - $20,000 +2%
Retail Space & Build-Out
$97,800 - $587,000 $163,000 - $978,300 -40%
Initial Inventory
$100,000 - $600,000 $100,000 - $600,000 Same
Pharmacy Equipment & Technology
$30,000 - $150,000 $30,000 - $150,000 Same
Insurance & Bonding
$8,000 - $25,000 $8,000 - $25,000 Same
Initial Staffing & Training
$23,000 - $92,000 $30,400 - $121,600 -24%
Marketing & Launch
$5,000 - $20,000 $5,000 - $20,000 Same
Working Capital (3 Months)
$53,900 - $215,600 $89,900 - $359,600 -40%
Total Estimated Cost $323,000 - $1,710,000 $431,000 - $2,275,000 -25%

Local Market Factors

Factor Chicago San Francisco
Cost of Living Index 107.8 179.8
Commercial Rent ($/sqft/yr) $25 - $65 $40 - $110
Labor Rate Index 1.15 1.52
Sales Tax 10.25% 8.625%
Minimum Wage $15.80/hr $18.67/hr
LLC Filing Fee $150 $70

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